Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | PTPRB | P23467 | 1/20 | 0.75 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.73 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.73 |
| ▸ | TNF | P01375 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941123 | 0.94 | RORC (0.77) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL14919686 | 0.94 | RORC (0.77) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941130 | 0.88 | MAPT (0.71) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941122 | 0.88 | TNF (0.82) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941129 | 0.88 | RORC (0.74) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6037137 | 0.86 | POLB (0.80) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL15798277 | 0.84 | CDK5 (1.00) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941140 | 0.84 | MAPT (0.72) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941133 | 0.82 | MAPT (0.78) | RORCKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL13941127 | 0.80 | TNF (0.69) | RORCKMT2AMEN1TNFCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016081-A2 | BENZOIND0L-2-ONE DERIVATIVES FOR USE IN THERAPY | ACTAR AB (SE) | 2009-02-05 | — | — | WO | disclosed |