Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.75 |
| ▸ | RAF1 | P04049 | 3/20 | 0.75 |
| ▸ | LYN | P07948 | 3/20 | 0.75 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.75 |
| ▸ | SRC | P12931 | 2/20 | 0.75 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.53 |
| ▸ | TNF | P01375 | 6/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.50 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | MUSK | O15146 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | STK10 | O94804 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527345 | 0.94 | ABL1 (0.76) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL13941119 | 0.93 | ABL1 (0.86) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL13527343 | 0.92 | SRC (0.71) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL13941131 | 0.90 | ABL1 (0.71) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL4091524 | 0.87 | ABL1 (0.88) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL4096870 | 0.87 | ABL1 (0.85) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL4557827 | 0.86 | ABL1 (0.84) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL3185172 | 0.86 | ABL1 (1.00) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL4087857 | 0.86 | ABL1 (0.72) | ABL1RAF1LYNMAPK9SRC | |
| SCHEMBL4086140 | 0.85 | ABL1 (0.88) | ABL1RAF1LYNMAPK9SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | JUNG BIRGIT | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | BDKRB2, EDNRB, GRK5 | ABL1 1152/4885RAF1 300/4885LYN 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.