Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941829 | 1.00 | TP53 (0.68) | TP53TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13942114 | 0.90 | TP53 (0.71) | TP53TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13941342 | 0.90 | TP53 (0.71) | TP53TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3494747 | 0.89 | MEN1 (0.61) | TP53TSHRALDH1A1ALOX5APKMT2A | |
| SCHEMBL3235521 | 0.89 | MEN1 (0.61) | TP53TSHRALDH1A1ALOX5APKMT2A | |
| SCHEMBL13942115 | 0.87 | TSHR (0.74) | TP53TSHRMAPTALDH1A1ALOX5AP | |
| SCHEMBL13942117 | 0.86 | ALOX5AP (0.65) | TP53TSHRMAPTALOX5APKMT2A | |
| SCHEMBL12391809 | 0.78 | TSHR (0.52) | TP53TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1038904 | 0.78 | TSHR (0.52) | TP53TSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4083319 | 0.78 | TP53 (0.63) | TP53MAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019014-A1 | NOVEL BENZIMIDAZOL-2-YL-ALKYLAMINES AND THE USE THEREOF AS MICROBICIDAL AGENTS | EMC MICROCOLLECTIONS GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |