Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169953 | 0.87 | LMNA (0.70) | TP53MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL31633144 | 0.85 | TSHR (0.66) | TP53MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL30897361 | 0.85 | TP53 (0.60) | TP53MAPTSMN1; SMN2KMT2ARCE1 | |
| SCHEMBL10353116 | 0.84 | KMT2A (0.76) | TP53MAPTSMN1; SMN2KMT2ARCE1 | |
| SCHEMBL4097969 | 0.84 | NOD1 (0.71) | TP53MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL28322548 | 0.83 | TP53 (0.71) | TP53MAPTSMN1; SMN2KMT2ARCE1 | |
| SCHEMBL13942114 | 0.83 | TP53 (0.71) | TP53MAPTSMN1; SMN2KMT2ARCE1 | |
| SCHEMBL4083091 | 0.82 | SOS1 (0.57) | TP53MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL30897396 | 0.82 | TP53 (0.60) | TP53MAPTSMN1; SMN2KMT2ARCE1 | |
| Hydrochloric Acid SCHEMBL10353237 | 0.82 | TP53 (0.57) | TP53MAPTSMN1; SMN2KMT2ARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062317-A1 | MEDICINAL USE OF RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2009-03-05 | — | — | US | disclosed |
| EP-1778670-A2 | MEDICINAL USE OF RECEPTOR LIGANDS | 7TM Pharma A/S (DK) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006010446-A2 | MEDICINAL USE OF RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062317-A1 | MEDICINAL USE OF RECEPTOR LIGANDS | MCHR1, MCHR2, MC1R | TP53 4783/4885MAPT 4135/4885SMN1; SMN2 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.