Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 8/20 | 1.00 |
| ▸ | CCND1 | P24385 | 8/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942343 | 0.89 | CDK4 (1.00) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL9936105 | 0.88 | CDK4 (0.79) | CDK4CCND1PTGS2POLBKMT2A | |
| SCHEMBL13942335 | 0.88 | CDK4 (0.83) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL13942356 | 0.86 | CDK4 (1.00) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL28928726 | 0.84 | PTGS2 (1.00) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL28656689 | 0.82 | POLB (0.71) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL13942344 | 0.81 | CDK4 (1.00) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL28645297 | 0.81 | POLB (0.70) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL4603547 | 0.81 | CDK4 (0.68) | CDK4CCND1PTGS2NPC1POLB | |
| SCHEMBL28638912 | 0.79 | PTGS2 (0.74) | CDK4CCND1PTGS2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009022104-A1 | FASCAPLYSIN DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | DE MONTFORT UNIVERSITY (GB) | 2009-02-19 | — | — | WO | disclosed |