Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651845 | 1.00 | GHSR (0.46) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL3643558 | 0.87 | GHSR (0.44) | GHSR | |
| SCHEMBL13942541 | 0.87 | GHSR (0.44) | GHSR | |
| SCHEMBL13943096 | 0.84 | CHRNB4 (0.44) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL3646824 | 0.84 | CHRNB4 (0.44) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL13943090 | 0.82 | CHRNB4 (0.42) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL3644382 | 0.82 | CHRNB4 (0.42) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL14474354 | 0.81 | GHSR (0.41) | GHSR | |
| SCHEMBL3762400 | 0.72 | GHSR (0.44) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL3651613 | 0.70 | TAAR1 (0.43) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016048-A1 | 2-AZETIDINEMETHANEAMINES AND 2-PYRROLIDINEMETHANEAMINES AS TAAR-LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |