Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922607 | 0.92 | F3 (0.32) | F3F2 | |
| SCHEMBL11991471 | 0.85 | LTC4S (0.33) | GAAPTGER4 | |
| SCHEMBL11922602 | 0.81 | SCN9A (0.32) | SCN9A | |
| SCHEMBL11922631 | 0.81 | GRM2 (0.30) | — | |
| SCHEMBL11922578 | 0.80 | HIF1A (0.37) | KCNH2SCN9A | |
| SCHEMBL11922627 | 0.79 | PTGER4 (0.35) | F3SCN9AGAAPTGER4 | |
| SCHEMBL11922621 | 0.78 | PTGER4 (0.34) | F3F2SCN9AGAAPTGER4 | |
| SCHEMBL13044775 | 0.78 | GAA (0.34) | F3F2SCN9AGAA | |
| SCHEMBL11991523 | 0.78 | F3 (0.31) | KCNH2F3F2GAA | |
| SCHEMBL11991470 | 0.77 | DHODH (0.34) | KCNH2F3SCN9AASPHPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018657-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |