Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922595 | 0.91 | PTK2 (0.34) | CFTRALDH1A1HPGDTSHRCASP1 | |
| SCHEMBL11922604 | 0.86 | KMT2A (0.35) | CFTRALDH1A1HPGDTSHRCASP1 | |
| SCHEMBL11922630 | 0.83 | SCN9A (0.33) | IRAK4KDM4ESCN9APTK2 | |
| SCHEMBL11991478 | 0.83 | PTK2 (0.32) | CFTRRIPK1SCN9APTK2 | |
| SCHEMBL11991528 | 0.82 | PTK2 (0.33) | CFTRRIPK1MAPTSCN9APTK2 | |
| SCHEMBL11991472 | 0.79 | KMT2A (0.34) | CFTRIRAK4MBOAT4NR1H2RIPK1 | |
| SCHEMBL13044755 | 0.79 | CFTR (0.46) | CFTRALDH1A1MBOAT4RIPK1MAPT | |
| SCHEMBL11992926 | 0.78 | KMT2A (0.34) | CFTRALDH1A1HPGDHSD17B10NR1H2 | |
| SCHEMBL13947015 | 0.78 | PTK2 (0.38) | CFTRALDH1A1HSD17B10IRAK4RIPK1 | |
| SCHEMBL11991450 | 0.78 | PTK2 (0.36) | CFTRRIPK1SCN9APTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018657-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |