Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | BCDIN3D | Q7Z5W3 | 16/20 | 0.60 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947571 | 0.90 | PDE2A (0.67) | TP53MAPTBCDIN3DPDE2A | |
| SCHEMBL13944752 | 0.90 | TP53 (0.74) | TP53MAPTHTR2CBCDIN3D | |
| SCHEMBL13942974 | 0.86 | HTR2C (0.64) | HTR2CBCDIN3DPDE2A | |
| SCHEMBL13946785 | 0.83 | HTR2C (0.60) | HTR2CBCDIN3DPDE2A | |
| SCHEMBL13942972 | 0.82 | HTR2C (0.65) | HTR2CBCDIN3DPDE2A | |
| SCHEMBL13943267 | 0.81 | BCDIN3D (0.58) | HTR2CBCDIN3D | |
| SCHEMBL13942967 | 0.80 | MAPT (0.66) | TP53MAPTHTR2CBCDIN3D | |
| SCHEMBL13947030 | 0.79 | MAPK1 (0.57) | HTR2CBCDIN3D | |
| SCHEMBL13942956 | 0.78 | MAPT (0.79) | TP53MAPTHTR2CBCDIN3D | |
| SCHEMBL23598913 | 0.78 | PDE2A (0.83) | TP53HTR2CBCDIN3DPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023978-A1 | PYRAZOLO [3,4 -D] PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF PROTEIN KINASE | ONCALIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |