Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | BCDIN3D | Q7Z5W3 | 14/20 | 0.62 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944705 | 0.90 | TP53 (0.64) | PDE2ATP53MAPTBCDIN3D | |
| SCHEMBL13944752 | 0.89 | TP53 (0.74) | TP53MAPTBCDIN3D | |
| SCHEMBL13944372 | 0.86 | MAPT (0.80) | TP53MAPTBCDIN3D | |
| SCHEMBL13947033 | 0.85 | PDE2A (0.67) | PDE2ATP53BCDIN3DPLK4 | |
| SCHEMBL13947561 | 0.84 | PDE2A (0.76) | PDE2ATP53BCDIN3DPLK4 | |
| SCHEMBL13947566 | 0.82 | PDE2A (0.62) | PDE2ATP53BCDIN3DPLK4 | |
| SCHEMBL13944370 | 0.78 | PDE2A (0.65) | PDE2ATP53BCDIN3DPLK4 | |
| SCHEMBL22805928 | 0.76 | BCDIN3D (1.00) | BCDIN3D | |
| SCHEMBL29582699 | 0.76 | BCDIN3D (1.00) | BCDIN3D | |
| SCHEMBL13944173 | 0.76 | HTR2C (0.82) | PDE2ATP53MAPTBCDIN3DPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |