Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124584 | 0.92 | SLC6A2 (0.79) | SLC6A2HTR2ASLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL12124497 | 0.90 | SLC6A2 (0.70) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124608 | 0.83 | SLC6A2 (0.71) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124589 | 0.82 | HTR1A (0.77) | HTR1AHTR7 | |
| SCHEMBL12124499 | 0.81 | SLC6A2 (0.84) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124408 | 0.80 | SLC6A2 (1.00) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL16216950 | 0.80 | SLC6A2 (0.82) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL15958315 | 0.80 | SLC6A2 (0.82) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124501 | 0.80 | SLC6A2 (0.82) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124469 | 0.79 | SLC6A2 (0.98) | SLC6A2HTR2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026227-A2 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | THE UNIVERSITY OF MISSISSIPPI (US) | 2009-02-26 | — | — | WO | disclosed |