Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.80 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944194 | 0.94 | HTR2C (0.80) | HTR2CHTR2ABCDIN3D | |
| SCHEMBL13947563 | 0.92 | HTR2C (0.83) | HTR2CHTR2A | |
| SCHEMBL13943286 | 0.88 | HTR2C (0.85) | HTR2CHTR2ABCDIN3D | |
| SCHEMBL2861107 | 0.88 | HTR2C (0.85) | HTR2CHTR2ABCDIN3D | |
| SCHEMBL13946809 | 0.84 | HTR2C (0.68) | HTR2C | |
| SCHEMBL13944188 | 0.84 | HTR2C (0.82) | HTR2CHTR2ABCDIN3D | |
| SCHEMBL3756996 | 0.82 | HTR2C (1.00) | HTR2CHTR2A | |
| SCHEMBL13943676 | 0.82 | KDM4E (0.62) | HTR2CBCDIN3D | |
| SCHEMBL13944740 | 0.81 | HTR2C (0.81) | HTR2CHTR2A | |
| SCHEMBL13942982 | 0.81 | HTR2C (0.74) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |