Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944194 | 0.90 | HTR2C (0.80) | HTR2CPIK3CA | |
| SCHEMBL13942982 | 0.89 | HTR2C (0.74) | HTR2CPIK3CA | |
| SCHEMBL13947359 | 0.88 | HTR2C (0.62) | HTR2CLMNAPIK3CA | |
| SCHEMBL13947563 | 0.84 | HTR2C (0.83) | HTR2C | |
| SCHEMBL13947037 | 0.84 | HTR2C (0.80) | HTR2C | |
| SCHEMBL13943704 | 0.84 | HTR2C (0.60) | HTR2CPIK3CA | |
| SCHEMBL13943676 | 0.83 | KDM4E (0.62) | HTR2CPIK3CA | |
| SCHEMBL13944743 | 0.81 | HTR2C (0.82) | HTR2CPIK3CA | |
| SCHEMBL3756996 | 0.81 | HTR2C (1.00) | HTR2C | |
| SCHEMBL13946796 | 0.80 | HTR2C (0.58) | HTR2CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |