Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 17/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13948002 | 0.88 | CXCR2 (0.44) | CXCR2CXCR1 | |
| SCHEMBL13947697 | 0.84 | CXCR2 (0.53) | CXCR2CXCR1 | |
| SCHEMBL13207368 | 0.84 | CXCR2 (0.51) | CXCR2CXCR1 | |
| SCHEMBL13405743 | 0.84 | CXCR2 (0.50) | CXCR2CXCR1 | |
| SCHEMBL13947940 | 0.82 | CXCR2 (0.41) | CXCR2CXCR1 | |
| SCHEMBL13207252 | 0.80 | CXCR2 (0.49) | CXCR2CXCR1 | |
| SCHEMBL13947990 | 0.78 | CCR6 (0.43) | — | |
| SCHEMBL13207155 | 0.75 | CXCR2 (0.47) | CXCR2CXCR1 | |
| SCHEMBL13207367 | 0.75 | CXCR2 (0.55) | CXCR2CXCR1 | |
| SCHEMBL13948244 | 0.75 | CXCR2 (0.50) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |