Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947597 | 0.88 | CXCR2 (0.54) | CXCR2CXCR1 | |
| SCHEMBL14100579 | 0.87 | CXCR1 (0.51) | CXCR2CXCR1 | |
| SCHEMBL14100317 | 0.86 | CXCR1 (0.59) | CXCR2CXCR1 | |
| SCHEMBL14100216 | 0.86 | CXCR2 (0.51) | CXCR2CXCR1 | |
| SCHEMBL13947684 | 0.84 | CXCR2 (0.40) | CXCR2CXCR1 | |
| SCHEMBL13207006 | 0.83 | CXCR1 (0.70) | CXCR2CXCR1 | |
| SCHEMBL27128903 | 0.83 | CXCR1 (0.70) | CXCR2CXCR1 | |
| SCHEMBL13207188 | 0.83 | CXCR2 (0.70) | CXCR2CXCR1 | |
| SCHEMBL13948002 | 0.83 | CXCR2 (0.44) | CXCR2CXCR1 | |
| SCHEMBL13227096 | 0.82 | CXCR2 (0.58) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |