Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 14/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439877 | 0.90 | CXCR2 (0.52) | CXCR2CXCR1 | |
| SCHEMBL13407234 | 0.85 | CCR6 (0.54) | CXCR2CXCR1 | |
| SCHEMBL13439798 | 0.81 | CXCR2 (0.51) | CXCR2CXCR1 | |
| SCHEMBL13439875 | 0.81 | CXCR2 (0.54) | CXCR2CXCR1 | |
| SCHEMBL13440163 | 0.80 | CXCR2 (0.56) | CXCR2CXCR1 | |
| SCHEMBL13407252 | 0.79 | CCR6 (0.51) | CXCR2CXCR1 | |
| SCHEMBL13406874 | 0.79 | CXCR2 (0.61) | CXCR2CXCR1 | |
| SCHEMBL13407232 | 0.78 | CXCR2 (0.53) | CXCR2CXCR1 | |
| SCHEMBL13440165 | 0.78 | CXCR1 (0.55) | CXCR2CXCR1 | |
| SCHEMBL13407355 | 0.77 | CCR6 (0.53) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |