Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904633 | 1.00 | MMP2 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL3953990 | 1.00 | MMP2 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL3948953 | 0.93 | NPC1 (0.41) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL13904587 | 0.93 | NPC1 (0.41) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL3954188 | 0.93 | NPC1 (0.39) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL13904595 | 0.93 | NPC1 (0.39) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL13904615 | 0.93 | TRPV1 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL3948650 | 0.93 | TRPV1 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL3947574 | 0.92 | TRPV1 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 | |
| SCHEMBL13904598 | 0.92 | TRPV1 (0.38) | MMP2MMP9TRPV1CDK2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025669-A1 | Alpha-alkyl substituted N-acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-18 | — | — | EP | disclosed |