Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | AKT2 | P31751 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769174 | 0.97 | KDM4E (0.75) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL22769176 | 0.97 | KDM4E (0.75) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL13726198 | 0.97 | KDM4E (0.75) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL24590007 | 0.97 | KDM4E (0.75) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL29382173 | 0.97 | KDM4E (0.74) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL732131 | 0.97 | KDM4E (0.74) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL865711 | 0.94 | KDM4E (0.71) | KDM4EL3MBTL1LMNAGAATDP1 | |
| Water SCHEMBL27680271 | 0.94 | KDM4E (0.71) | KDM4EL3MBTL1LMNAGAATDP1 | |
| SCHEMBL28710728 | 0.94 | KDM4E (0.71) | KDM4EL3MBTL1LMNAGAATDP1 | |
| Bromide SCHEMBL27580121 | 0.92 | KDM4E (0.68) | KDM4EL3MBTL1LMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640402-B1 | DIAMINE HAVING QUINOXALINE UNIT, POLYIMIDE PRECURSOR, POLYIMIDE AND USE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2009-02-11 | — | — | EP | disclosed |