SCHEMBL732131

SCHEMBL732131

c1ccc(-c2nc3ccccc3nc2-c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.74
L3MBTL1 Q9Y468 6/20 0.74
LMNA P02545 5/20 0.74
TDP1 Q9NUW8 3/20 0.74
GAA P10253 3/20 0.74
KMT2A Q03164 3/20 0.74
MEN1 O00255 2/20 0.74
PKM P14618 1/20 0.70
ALDH1A1 P00352 5/20 0.65
NPSR1 Q6W5P4 1/20 0.65
ATM Q13315 1/20 0.61
TLR9 Q9NR96 1/20 0.61
AKT1 P31749 1/20 0.61
AKT2 P31751 1/20 0.61
THRB P10828 1/20 0.57
PDE10A Q9Y233 1/20 0.56
MAPT P10636 1/20 0.56
NPC1 O15118 1/20 0.55
HPGD P15428 1/20 0.55
RAB9A P51151 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382173 1.00 KDM4E (0.74) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL865711 0.97 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL13950894 0.97 KDM4E (0.78) KDM4EL3MBTL1LMNATDP1GAA
Water SCHEMBL27680271 0.97 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL28710728 0.97 KDM4E (0.71) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL24590007 0.95 KDM4E (0.75) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL13726198 0.95 KDM4E (0.75) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL22769174 0.95 KDM4E (0.75) KDM4EL3MBTL1LMNATDP1GAA
SCHEMBL22769176 0.95 KDM4E (0.75) KDM4EL3MBTL1LMNATDP1GAA
Bromide SCHEMBL27580121 0.95 KDM4E (0.68) KDM4EL3MBTL1LMNATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP claimed
WO-2025024934-A1 COLOUR CHANGING ELECTROCHROMIC DEVICE AND METHOD OF MANUFACTURING THEREOF TRUSSCORE INC. (CA) 2025-02-06 WO claimed
US-20240316012-A1 METHODS FOR TREATING LYMPHOMA NORTHWESTERN UNIVERSITY (US) 2024-09-26 US claimed
CN-118480146-A Preparation method of polyprenol-based light-controlled antibacterial synergist 中国林业科学研究院林产化学工业研究所 2024-08-13 CN claimed
US-20240219403-A1 METHODS FOR INHIBITING KRAS ONCOPROTEIN THROUGH ENHANCED GTPASE ACTIVITY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-07-04 US claimed
EP-4363043-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2024-05-08 EP claimed
CN-117580614-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2024-02-20 CN claimed
CN-116390760-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2023-07-04 CN claimed
EP-4188380-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2023-06-07 EP claimed
US-20230001193-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS BIOPHARMA CREDIT PLC (GB) 2023-01-05 US claimed
US-20050106416-A1 Process for preparing crosslinked polymer blends that include a luminescent polymer LUMERA CORPORATION 2005-05-19 US claimed
US-20050106417-A1 Crosslinked polymer blends that include a luminescent polymer, and devices incorporating same LUMERA CORPORATION 2005-05-19 US claimed
CN-1352809-A Conductive polymers QINITIK CO LTD (GB) 2002-06-05 CN claimed
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US claimed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP claimed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US claimed