SCHEMBL1395294

SCHEMBL1395294

CCCCCCCCCCC1(CCCCCCCCCC)c2ccccc2-c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.47
MMP2 P08253 4/20 0.46
MMP9 P14780 4/20 0.46
MMP8 P22894 2/20 0.46
MMP13 P45452 2/20 0.46
PDK2 Q15119 3/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MMP3 P08254 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTPN1 P18031 1/20 0.38
ELANE P08246 1/20 0.38
PGR P06401 1/20 0.37
CES1 P23141 2/20 0.37
CDC25A P30304 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29453552 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL1681761 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL6060794 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL6060689 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL6060635 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL6060916 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL14736023 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL1395156 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL17034549 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13
SCHEMBL30536393 1.00 APEX1 (0.47) APEX1MMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929878-A Copolymer of EDOT and (hetero) arene and application thereof 成都信息工程大学 2022-01-14 CN claimed
CN-113817141-A Copolymer of EDOT and (hetero) arene and preparation method thereof 成都信息工程大学 2021-12-21 CN claimed
CN-110437425-A Super-hydrophobic porous organic polymer containing alkyl chain of one kind and its preparation method and application UNIV LIAONING 2019-11-12 CN claimed
CN-113929878-A Copolymer of EDOT and (hetero) arene and application thereof 成都信息工程大学 2022-01-14 CN disclosed
CN-113817141-A Copolymer of EDOT and (hetero) arene and preparation method thereof 成都信息工程大学 2021-12-21 CN disclosed
CN-105392824-B The preparation method of new branch oligomeric aryl-silane and they 发光创新科技有限责任公司 2018-09-28 CN disclosed
EP-3039728-B1 POLYMERIC ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2018-07-04 EP disclosed
EP-2586809-B1 POLYMER CONTAINING UNITS OF FLUORENE, ANTHRACENE AND BENZOTHIADIAZOLE, PREPARATION METHOD AND USES THEREOF OCEAN S KING LIGHTING SCIENCE&TECHNOLOGY CO LTD (CN) 2016-08-10 EP disclosed
CN-105392824-A Novel branched oligoarylsilanes and method for producing same LUMINESCENT INNOVATION TECH LLC 2016-03-09 CN disclosed
CN-103153953-B Organic semiconductor material, preparation methods and uses thereof OCEANS KING LIGHTING SCIENCE 2015-03-11 CN disclosed
CN-103154002-B Organic semiconductor material, preparation methods and uses thereof OCEANS KING LIGHTING SCIENCE 2015-01-07 CN disclosed
WO-2004072205-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-08-26 WO disclosed
US-20030065226-A1 Method for preparing bromofluorenes ADCHEMCO CORPORATION (JP) 2003-04-03 US disclosed
EP-1298117-A2 Method for preparing bromofluorenes Adchemco Corporation (JP) 2003-04-02 EP disclosed
CN-1404346-A Organic EL element and method for manufacturing the same TDK CORP (JP) 2003-03-19 CN disclosed
US-20030044645-A1 Organic EL device and preparation method TDK CORPORATION (JP) 2003-03-06 US disclosed
US-6528942-B1 Organic electroluminescence device, its manufacturing method and board for display device used therefor ROHM CO., LTD. (JP) 2003-03-04 US disclosed
EP-1285957-A2 Organic electroluminescent device and method of its preparation TDK Corporation (JP) 2003-02-26 EP disclosed
US-5859251-A SYMMETRICAL CHROMOPHORES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1999-01-12 US disclosed
US-5770737-A FLUORESCENT IMAGING THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1998-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065226-A1 Method for preparing bromofluorenes FLNB, AFF2, BRPF1 APEX1 1019/4885MMP2 3462/4885MMP9 2286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.