Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430794 | 0.91 | MAOB (0.60) | MAOBLMNARAB9ACCR5USP2 | |
| SCHEMBL4430797 | 0.91 | MAOB (0.60) | MAOBLMNARAB9ACCR5USP2 | |
| SCHEMBL13886069 | 0.91 | MAOB (0.60) | MAOBLMNARAB9ACCR5USP2 | |
| SCHEMBL14206846 | 0.89 | MAOB (0.65) | MAOBLMNAMAPTALDH1A1RECQL | |
| SCHEMBL13956250 | 0.88 | MAOB (0.58) | MAOBLMNACYP1A2CYP3A4MAPT | |
| SCHEMBL13956196 | 0.85 | MAOB (0.57) | MAOBCCR5MAOA | |
| SCHEMBL13971180 | 0.80 | HPGD (0.45) | MAOBLMNACYP1A2CYP3A4MAPT | |
| SCHEMBL1878476 | 0.79 | HPGD (0.50) | MAOBLMNAMAPTALDH1A1 | |
| SCHEMBL31611218 | 0.77 | LMNA (0.48) | MAOBLMNACYP1A2CYP3A4MAPT | |
| SCHEMBL13785972 | 0.77 | MAOB (0.62) | MAOBMAPTALDH1A1RECQLMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | MAOB 457/4885LMNA 1163/4885CYP1A2 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.