Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850967 | 0.89 | ALDH1A1 (0.88) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL29386186 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| SCHEMBL11699567 | 0.84 | ALDH1A1 (0.74) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| SCHEMBL11865373 | 0.84 | ALDH1A1 (0.89) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| SCHEMBL9958244 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL6561910 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL1517385 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL5490 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL3290495 | 0.83 | CYP3A4 (0.92) | CYP3A4TSHRALDH1A1HPGDRAB9A | |
| Piperonyl Butoxide SCHEMBL9155914 | 0.82 | CYP3A4 (0.97) | CYP3A4TSHRALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467020-B1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA SPA (IT) | 2014-09-24 | — | — | EP | disclosed |
| US-8809389-B2 | Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-08-19 | — | — | US | disclosed |
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ROTHAMSTED RESEARCH LTD. | 2012-08-16 | — | — | US | disclosed |
| EP-2289889-A1 | Substituted alkynyl phenoxy compounds and their uses | Endura S.p.a. (IT) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | DDT, PYM1, CHRM1 | CYP3A4 340/4885TSHR 1145/4885ALDH1A1 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.