SCHEMBL13961192

SCHEMBL13961192

CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1nc2ccc(NC(=O)c3ncsc3-c3ccc(C(C)(C)C)cc3)cc2s1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4939193 0.88 MTTP (0.69) MTTP
SCHEMBL4939201 0.88 MTTP (0.69) MTTP
SCHEMBL14027933 0.88 MTTP (0.69) MTTP
SCHEMBL3943013 0.86 MTTP (0.58) MTTP
SCHEMBL14027947 0.85 MTTP (0.58) MTTP
SCHEMBL14027988 0.84 MTTP (0.57) MTTP
SCHEMBL14027828 0.83 MTTP (0.54) MTTP
SCHEMBL14027931 0.82 MTTP (0.69) MTTP
SCHEMBL4933801 0.81 MTTP (0.54) MTTP
SCHEMBL4933796 0.81 MTTP (0.54) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009014674-A1 HETEROCYCLYLAMIDES AS GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS SIRTRIS PHARMACEUTICALS, INC. (US) 2009-01-29 — — WO disclosed
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