Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939201 | 0.91 | MTTP (0.69) | MTTP | |
| SCHEMBL4939193 | 0.91 | MTTP (0.69) | MTTP | |
| SCHEMBL14027933 | 0.91 | MTTP (0.69) | MTTP | |
| SCHEMBL14027947 | 0.89 | MTTP (0.58) | MTTP | |
| SCHEMBL14027988 | 0.88 | MTTP (0.57) | MTTP | |
| SCHEMBL14027931 | 0.86 | MTTP (0.69) | MTTP | |
| SCHEMBL13961192 | 0.86 | MTTP (0.53) | MTTP | |
| SCHEMBL14027919 | 0.84 | MTTP (0.59) | MTTP | |
| SCHEMBL4938961 | 0.83 | MTTP (0.68) | MTTP | |
| SCHEMBL4938968 | 0.83 | MTTP (0.68) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009014674-A1 | HETEROCYCLYLAMIDES AS GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009014674-A1 | HETEROCYCLYLAMIDES AS GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |