Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 2/20 | 0.30 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962141 | 0.83 | ADRB3 (0.39) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL8293914 | 0.83 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CNAAAALOX15 | |
| SCHEMBL2633296 | 0.81 | ADRB3 (0.38) | ADRB3ADRA2BADRA2CNAAAXIAP | |
| SCHEMBL12785318 | 0.79 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CNAAA | |
| SCHEMBL7940240 | 0.79 | ADRB3 (0.39) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL8129662 | 0.78 | ADRB3 (0.43) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL1683122 | 0.78 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CNAAAALOX15 | |
| SCHEMBL8005984 | 0.78 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CNAAAALOX15 | |
| SCHEMBL13059221 | 0.78 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CNAAAALOX15 | |
| SCHEMBL1645088 | 0.78 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CNAAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005565-A9 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES INC (US) | 2009-01-29 | — | — | WO | disclosed |