Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 1.00 |
| ▸ | P2RY13 | Q9BPV8 | 4/20 | 1.00 |
| ▸ | PLA2G2A | P14555 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.64 |
| ▸ | YWHAG | P61981 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361087 | 0.85 | P2RY1 (1.00) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL13961829 | 0.85 | P2RY1 (1.00) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL13961828 | 0.85 | P2RY1 (0.74) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL3361094 | 0.84 | P2RY1 (0.98) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL13961318 | 0.84 | P2RY1 (0.73) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| Water SCHEMBL31722292 | 0.84 | P2RY1 (0.97) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL7091376 | 0.83 | P2RY1 (0.71) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL7091071 | 0.83 | P2RY1 (0.73) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL7094651 | 0.79 | P2RX7 (0.74) | P2RY1P2RY13PLA2G2AMEN1KMT2A | |
| SCHEMBL7090990 | 0.79 | P2RX7 (0.74) | P2RY1P2RY13PLA2G2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005469-A2 | THE USE OF COMPOUNDS SUCH AS PYRIDOXAL DERIVATIVES FOR THE TREATMENT OF DIABETES OR DISEASES ASSOCIATED WITH THE METABOLIC SYNDROME | ERLINGE DAVID (SE) | 2009-01-08 | — | — | WO | disclosed |