SCHEMBL1396313

SCHEMBL1396313

Fc1cc(-c2ncc[nH]2)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.38
MTOR P42345 1/20 0.38
ADK P55263 1/20 0.38
CSNK1A1 P48729 1/20 0.37
TYRO3 Q06418 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
CASP6 P55212 1/20 0.35
MC4R P32245 1/20 0.34
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMPD3 Q9NY59 1/20 0.34
F2RL1 P55085 5/20 0.33
KDM4E B2RXH2 2/20 0.33
ADRA2A P08913 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3060671 0.82 NISCH (0.44) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL1688637 0.76 NISCH (0.50) NISCHMTORADKALDH1A1MEN1
SCHEMBL1688439 0.73 CASP6 (0.47) NISCHMTORADKCASP6F2RL1
SCHEMBL11462 0.73 NISCH (0.45) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL1436578 0.72 CSNK1A1 (0.46) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL27863493 0.72 CASP6 (0.46) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL29985833 0.71 NISCH (0.53) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL1289114 0.71 NISCH (0.53) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL15082480 0.70 NISCH (0.55) NISCHMTORADKCSNK1A1TYRO3
SCHEMBL8536056 0.70 MC4R (0.49) NISCHMTORADKCSNK1A1TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11828660-B2 UV cured indicating devices JP LABORATORIES, INC. (US) 2023-11-28 US disclosed
EP-3293493-B1 STERILIZATION INDICATING DEVICE JP LABORATORIES INC (US) 2023-06-14 EP disclosed
US-20210322587-A1 Monitoring System Based on Etching of Metals JP LABORATORIES INC. 2021-10-21 US disclosed
US-11071795-B2 Indicating devices based on etching of metals JP LABORATORIES INC. (US) 2021-07-27 US disclosed
US-10451595-B2 Indicating devices based on lateral diffusion of a mobile phase through a non-porous stationary phase JP LABORATORIES, INC (US) 2019-10-22 US disclosed
US-20180259403-A1 UV Cured Indicating Devices JP LABORATORIES, INC. 2018-09-13 US disclosed
EP-3293493-A1 A MONITORING SYSTEM BASED ON ETCHING OF METALS Patel, G (US) 2018-03-14 EP disclosed
US-20180024011-A1 Indicating Devices Based on Etching of Metals JP LABORATORIES INC. 2018-01-25 US disclosed
EP-2288879-B1 A MONITORING SYSTEM BASED ON ETCHING OF METALS PATEL G (US) 2018-01-24 EP disclosed
US-20170261381-A1 Monitoring system based on etching of metals JP LABORATORIES (US) 2017-09-14 US disclosed
WO-2014210460-A1 TIME INDICATING DEVICES BASED ON COUNTERBALANCING REACTIONS JP LABORATORIES, INC. (US) 2014-12-31 WO disclosed
US-20140154808-A1 MONITORING SYSTEM BASED ON ETCHING OF METALS PATEL GORDHANBHAI N (US) 2014-06-05 US disclosed
US-8343437-B2 Monitoring system based on etching of metals JP LABORATORIES, INC. (US) 2013-01-01 US disclosed
EP-2288879-A1 A MONITORING SYSTEM BASED ON ETCHING OF METALS Patel, G (US) 2011-03-02 EP disclosed
US-20090301382-A1 Monitoring System Based on Etching of Metals JP LABORATORIES, INC 2009-12-10 US disclosed
WO-2009149243-A1 A MONITORING SYSTEM BASED ON ETCHING OF METALS PATEL G (US) 2009-12-10 WO disclosed
EP-1281080-A4 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LAB INC (US) 2006-03-22 EP disclosed
US-20030211618-A1 Color changing steam sterilization indicator JP LABORATORIES, INC. 2003-11-13 US disclosed
EP-1281080-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2003-02-05 EP disclosed
WO-2001086289-A1 COLOR CHANGING STEAM STERILIZATION INDICATOR JP LABORATORIES, INC. (US) 2001-11-15 WO disclosed