Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485454 | 0.82 | GNAI3 (0.60) | NPC1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL21309873 | 0.82 | DPP4 (0.43) | NPC1RAB9AALDH1A1TSHRGNAI3 | |
| SCHEMBL7490420 | 0.81 | GNAI3 (0.68) | NPC1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL13939945 | 0.81 | NPC1 (0.49) | NPC1RAB9AALDH1A1TSHRGNAI3 | |
| SCHEMBL8642325 | 0.79 | GNAI3 (0.71) | NPC1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL22147028 | 0.79 | GNAI3 (0.71) | NPC1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL10035 | 0.78 | NPC1 (0.52) | NPC1ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL12410266 | 0.78 | NPC1 (0.62) | NPC1RAB9AALDH1A1GNAI3GNAO1 | |
| SCHEMBL6437826 | 0.77 | NPC1 (0.55) | NPC1GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL13258370 | 0.77 | NPC1 (0.55) | NPC1GNAI3GNAO1GNAI1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023926-A1 | Trityl Derivatives for Enhancing Mass Spectrometry | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023926-A1 | Trityl Derivatives for Enhancing Mass Spectrometry | F3, TBCA, GYPA | NPC1 4649/4885RAB9A 4553/4885ALDH1A1 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.