Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13966628 | 1.00 | CA2 (0.51) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13941904 | 1.00 | CA2 (0.51) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13941902 | 1.00 | CA2 (0.51) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966152 | 0.85 | CA2 (0.47) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966352 | 0.85 | CA2 (0.47) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966124 | 0.85 | CA2 (0.47) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966900 | 0.84 | MCHR1 (0.43) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966840 | 0.84 | CA2 (0.51) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966348 | 0.81 | CA2 (0.45) | CA2CA9CA12ALDH1A1TSHR | |
| SCHEMBL13966122 | 0.81 | CA2 (0.45) | CA2CA9CA12ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012120-A1 | Synthesis of N-heterocycles, beta-amino acids, and allyl amines via aza-payne mediated reaction of ylides and hydroxy aziridines | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012120-A1 | Synthesis of N-heterocycles, beta-amino acids, and allyl amines via aza-payne mediated reaction of ylides and hydroxy aziridines | TET1, TET3, TET2 | CA2 2761/4885CA9 2506/4885CA12 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.