Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | RARG | P13631 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444258 | 0.89 | TSHR (0.54) | ALDH1A1TSHRTP53SRD5A2TDP1 | |
| SCHEMBL9681086 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL2126364 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL8653418 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL2615887 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL9339856 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL69167 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL69166 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL9681088 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG | |
| SCHEMBL9078494 | 0.79 | ALDH1A1 (0.68) | ALDH1A1FBP1RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011674-A1 | TRANS-1,2-DIPHENYLETHYLENE DERIVATIVES AND NANOSENSORS MADE THEREFROM | WESTERN MICHIGAN UNIVERSITY RESEARCH FOUNDATION (US) | 2009-01-22 | — | — | WO | disclosed |