Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25797838 | 0.95 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL24027612 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL17880835 | 0.91 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPTMEN1 | |
| SCHEMBL12390255 | 0.89 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRMAPTMEN1 | |
| SCHEMBL12510238 | 0.89 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL92146 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPTMEN1 | |
| SCHEMBL10817517 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRMAPTMEN1 | |
| SCHEMBL23710790 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL10816128 | 0.86 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL9638898 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8080622-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| WO-2009006285-A1 | SOLUBLE SILICONE PREPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-01-08 | — | — | WO | disclosed |