Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453277 | 0.95 | LTB4R (0.47) | LTB4RLTB4R2BRD4TSHR | |
| SCHEMBL13956434 | 0.95 | LTB4R (0.47) | LTB4RLTB4R2BRD4TSHR | |
| SCHEMBL4450768 | 0.91 | LTB4R (0.49) | LTB4RLTB4R2BRD4TSHR | |
| SCHEMBL4450879 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2TSHR | |
| SCHEMBL13971368 | 0.88 | TSHR (0.49) | LTB4RBRD4TSHR | |
| SCHEMBL13956435 | 0.87 | BRD4 (0.43) | LTB4RLTB4R2BRD4 | |
| SCHEMBL13956437 | 0.87 | LTB4R (0.41) | LTB4RLTB4R2BRD4 | |
| SCHEMBL2928705 | 0.86 | BRD4 (0.46) | LTB4RLTB4R2BRD4TSHR | |
| SCHEMBL13956428 | 0.86 | BRD4 (0.41) | LTB4RLTB4R2BRD4TSHR | |
| SCHEMBL2929677 | 0.85 | LTB4R (0.47) | LTB4RLTB4R2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |