Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13971180 | 0.89 | HPGD (0.45) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL14206353 | 0.88 | GAA (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL13786439 | 0.87 | MAOB (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL14035606 | 0.87 | GAA (0.46) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14221634 | 0.85 | MAOB (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL13971076 | 0.84 | GAA (0.46) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL14035636 | 0.82 | MAOB (0.40) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14035601 | 0.80 | CYP19A1 (0.45) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13956250 | 0.79 | MAOB (0.58) | MAPTMAOBCCR5LMNACYP1A2 | |
| SCHEMBL13663884 | 0.78 | GAA (0.47) | GAAALDH1A1MAPTMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | HPGD 57/4885GAA 15/4885ALDH1A1 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.