Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113589 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL17633769 | 0.81 | HPGD (0.64) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL17633768 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL10113858 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL17633820 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL8353967 | 0.75 | ALDH1A1 (0.74) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL10113552 | 0.74 | MAPT (0.46) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6164992 | 0.73 | ALDH1A1 (0.77) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL6164990 | 0.73 | ALDH1A1 (0.77) | ALDH1A1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL17633919 | 0.73 | ALDH1A1 (1.00) | ALDH1A1HPGDKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |