Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113451 | 0.96 | HDAC6 (0.53) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL10115026 | 0.84 | ALDH1A1 (0.68) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL10113440 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL10115072 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL10114996 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAHDAC6 | |
| SCHEMBL10113393 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL10114991 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL10115032 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL10113406 | 0.83 | HDAC3 (0.56) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL10113446 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |