Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13972908 | 0.80 | SMN1; SMN2 (0.59) | KMT2AEPHX2MEN1TSHRALDH1A1 | |
| SCHEMBL19463023 | 0.77 | KMT2A (0.50) | KMT2AEPHX2MEN1TSHRALDH1A1 | |
| SCHEMBL18208526 | 0.75 | KMT2A (0.56) | KMT2ATP53ALDH1A1HDAC3HDAC1 | |
| SCHEMBL18208524 | 0.75 | KMT2A (0.56) | KMT2ATP53ALDH1A1HDAC3HDAC1 | |
| SCHEMBL10114715 | 0.75 | KMT2A (0.46) | KMT2AEPHX2TP53TSHRLMNA | |
| SCHEMBL13204296 | 0.75 | KMT2A (0.46) | KMT2AEPHX2TP53TSHRLMNA | |
| SCHEMBL10114328 | 0.75 | NPY5R (0.55) | KMT2AEPHX2TP53MEN1TSHR | |
| SCHEMBL10133393 | 0.75 | NPY5R (0.55) | KMT2AEPHX2TP53MEN1TSHR | |
| SCHEMBL13716462 | 0.75 | RAB9A (0.64) | KMT2AALDH1A1LMNAHDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL18208696 | 0.74 | KMT2A (0.55) | KMT2ATP53ALDH1A1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |