Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12326596 | 0.87 | USP2 (0.58) | POLBUSP2MAPTALDH1A1TSHR | |
| SCHEMBL10114860 | 0.78 | USP2 (0.50) | POLBUSP2MAPTALDH1A1TSHR | |
| SCHEMBL14424278 | 0.78 | USP2 (0.50) | POLBUSP2MAPTALDH1A1TSHR | |
| SCHEMBL14424759 | 0.78 | USP2 (0.52) | POLBUSP2MAPTALDH1A1TSHR | |
| SCHEMBL10114473 | 0.78 | USP2 (0.52) | POLBUSP2MAPTALDH1A1TSHR | |
| SCHEMBL2357753 | 0.76 | ALDH1A1 (0.63) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6627142 | 0.75 | ALDH1A1 (0.65) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6627140 | 0.75 | ALDH1A1 (0.65) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL25042203 | 0.74 | NISCH (0.47) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL30279129 | 0.74 | NISCH (0.47) | MAPTALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |