SCHEMBL1397276

SCHEMBL1397276

COc1cccc2c(C#Cc3ccccc3)c3cccc(OC)c3c(C#Cc3ccccc3)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.50
GRM5 P41594 2/20 0.50
L3MBTL1 Q9Y468 6/20 0.42
EGFR P00533 2/20 0.41
TDP1 Q9NUW8 4/20 0.41
MAOA P21397 1/20 0.41
ATM Q13315 3/20 0.40
GRM4 Q14833 2/20 0.40
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
APP P05067 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL429875 0.95 KCNH2 (0.49) KCNH2GRM5L3MBTL1EGFRTDP1
SCHEMBL29368538 0.95 KCNH2 (0.49) KCNH2GRM5L3MBTL1EGFRTDP1
SCHEMBL15486254 0.95 KCNH2 (0.51) KCNH2GRM5L3MBTL1EGFRTDP1
SCHEMBL1470511 0.77 APP (0.44) KCNH2GRM5L3MBTL1TDP1ATM
SCHEMBL3803310 0.75 GRM5 (0.46) KCNH2GRM5L3MBTL1EGFRTDP1
SCHEMBL26259628 0.75 KCNH2 (0.51) KCNH2GRM5L3MBTL1EGFRTDP1
SCHEMBL30165319 0.74 APP (0.44) KCNH2GRM5L3MBTL1TDP1ATM
SCHEMBL551446 0.74 APP (0.44) KCNH2GRM5L3MBTL1TDP1ATM
SCHEMBL26259291 0.73 MAPT (0.53) KCNH2GRM5L3MBTL1EGFRPDGFRB
SCHEMBL29357652 0.73 APP (0.67) KCNH2GRM5L3MBTL1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662274-B2 Self-immolative polymers, articles thereof, and methods of making and using same GEORGIA TECH RESEARCH CORPORATION (US) 2020-05-26 US claimed
US-20180155483-A1 SELF-IMMOLATIVE POLYMERS, ARTICLES THEREOF, AND METHODS OF MAKING AND USING SAME GEORGIA TECH RESEARCH CORPORATION 2018-06-07 US claimed
US-5374500-A Positive photoresist composition containing photoacid generator and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-12-20 US claimed
US-5055439-A PHOTOACID GENERATING COMPOSITION AND SENSITIZER THEREFOR INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-10-08 US claimed
EP-0435531-A2 Photoacid generating composition and sensitizer therefor International Business Machines Corporation (US) 1991-07-03 EP claimed
JP-3200257-A None JP disclosed
US-11988963-B2 Low temperature cure photoimageable dielectric compositions and methods of their use NAWROCKI DANIEL J (US) 2024-05-21 US disclosed
US-11773252-B1 Transient polymer blends MORSECORP, Inc. (US) 2023-10-03 US disclosed
US-20220146936-A1 LOW TEMPERATURE CURE PHOTOIMAGEABLE DIELECTRIC COMPOSITIONS AND METHODS OF THEIR USE NAWROCKI DANIEL J (US) 2022-05-12 US disclosed
US-20210163731-A1 TRANSIENT POLYMER FORMULATIONS, ARTICLES THEREOF, AND METHODS OF MAKING AND USING SAME GEORGIA TECH RESEARCH CORPORATION 2021-06-03 US disclosed
EP-3253735-B1 LATENT ACIDS AND THEIR USE BASF SE (DE) 2021-03-31 EP disclosed
US-10662274-B2 Self-immolative polymers, articles thereof, and methods of making and using same GEORGIA TECH RESEARCH CORPORATION (US) 2020-05-26 US disclosed
EP-1769286-A2 OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-04 EP disclosed
WO-2006008250-A2 OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO disclosed
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed
US-5338818-A Silicon containing positive resist for DUV lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-08-16 US disclosed
US-5272042-A Positive photoresist system for near-UV to visible imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-12-21 US disclosed
US-5055439-A PHOTOACID GENERATING COMPOSITION AND SENSITIZER THEREFOR INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-10-08 US disclosed
JP-H03200257-A PHOTOSENSITIVE ACID GENERATING COMPOSITION AND SENSITIZER THEREFOR INTERNATL BUSINESS MACH CORP <IBM> 1991-09-02 JP disclosed
EP-0435531-A2 Photoacid generating composition and sensitizer therefor International Business Machines Corporation (US) 1991-07-03 EP disclosed