SCHEMBL551446

SCHEMBL551446

Clc1cccc2c(C#Cc3ccccc3)c3cccc(Cl)c3c(C#Cc3ccccc3)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 5/20 0.38
CYP2A6 P11509 3/20 0.38
GRM4 Q14833 4/20 0.36
MAPT P10636 2/20 0.36
KCNH2 Q12809 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
ADORA2A P29274 1/20 0.35
GRM5 P41594 2/20 0.34
DYRK1A Q13627 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30165319 1.00 APP (0.44) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL29365692 0.95 APP (0.43) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL20454318 0.95 APP (0.43) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL432731 0.95 APP (0.43) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL427566 0.94 APP (0.46) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL3623354 0.91 APP (0.36) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL11878344 0.86 CYP1A2 (0.41) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL15065239 0.85 GRM4 (0.36) APPL3MBTL1ATMTDP1GRM4
SCHEMBL4143563 0.85 APP (0.34) APPL3MBTL1ATMTDP1CYP1A2
SCHEMBL1470511 0.78 APP (0.44) APPL3MBTL1ATMTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4352449-B1 PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT CYALUME TECH INC (US) 2025-05-07 EP claimed
US-11940253-B2 Projectile payload for training ammunition with multi-spectral output CYALUME TECHNOLOGIES, INC. (US) 2024-03-26 US claimed
US-20230194226-A1 Projectile payload for training ammunition with multi-spectral output PNC BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2023-06-22 US claimed
EP-2630215-B1 COMBINED THERMAL AND CHEMILUMINESCENT REACTION SYSTEM CYALUME TECH INC (US) 2017-08-02 EP claimed
US-9587173-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2017-03-07 US claimed
EP-2459674-B1 COMBINED THERMAL AND CHEMILUMINESCENT REACTION SYSTEM CYALUME TECHNOLOGIES INC (US) 2016-07-13 EP claimed
US-20150368555-A1 CHEMILUMINESCENT SYSTEM GREAT ROCK CAPITAL PARTNERS MANAGEMENT, LLC, AS AGENT 2015-12-24 US claimed
US-9115306-B2 Low temperature oxalate systems and methods for chemiluminescent reactions CYALUME TECHNOLOGIES, INC. (US) 2015-08-25 US claimed
US-9116147-B2 Compositions and methods for detection of small molecules using dyes derivatized with analyte responsive receptors in a chemiluminescent assay BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-08-25 US claimed
US-9109156-B2 Chemiluminescent system IMPERIAL TOY LLC (US) 2015-08-18 US claimed
US-20100055713-A1 CHEMILUMINESCENCE SENSOR ARRAY SUNDARARAJAN NARAYAN 2010-03-04 US claimed
US-20100022023-A1 Pressure activatable chemiluminescent system useful for covert intrusion detection PNC BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2010-01-28 US claimed
US-7537934-B2 For monitoring molecular binding; integrated assay device comprising chemiluminescent material, biopolymer and a light detector; identify antigen binding to antibodies INTEL CORPORATION (US) 2009-05-26 US claimed
US-20080308776-A1 CHEMILUMINESCENT COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF MEGA GLOW, LLC 2008-12-18 US claimed
US-20070154967-A1 For monitoring molecular binding; integrated assay device comprising chemiluminescent material, biopolymer and a light detector; identify antigen binding to antibodies INTEL CORPORATION (US) 2007-07-05 US claimed
US-20050007760-A1 Multi-color chemiluminescent light device WU LI-FU (TW) 2005-01-13 US claimed
US-5705103-A Composition for producing chemiluminescent light of controllable duration JAME FINE CHEMICALS, INC. (US) 1998-01-06 US claimed
US-5607864-A USED IN IMMUNOLOGICAL ANALYSIS SOCIETE PROLABO (FR) 1997-03-04 US claimed
US-5597517-A OXALATE ESTER, SOLVENT, ACTIVATOR, FLUORESCER JAME FINE CHEMICALS, INC. (US) 1997-01-28 US claimed
US-5281367-A Oxalate ester and solvent, peroxide and solvent, fluorescer, magnesium containing catalyst JAME FINE CHEMICALS, INC. (US) 1994-01-25 US claimed