Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279090 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL240100 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL29209046 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL13105202 | 0.79 | MAPT (0.40) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL23262627 | 0.78 | ALDH1A1 (0.33) | ALDH1A1GAAMAPTKMT2ATSHR | |
| SCHEMBL30336472 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL24864947 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL11941020 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL29208999 | 0.75 | PIK3CA (0.43) | ALDH1A1KDM4EGAANPSR1HTT | |
| SCHEMBL29209033 | 0.75 | PIK3CA (0.43) | ALDH1A1KDM4EGAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |