Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425691 | 1.00 | GRIN2C (0.43) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4422268 | 0.83 | GRIN2C (0.55) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL6505108 | 0.81 | GRIN2C (0.40) | GRIN2CMTNR1BCA12CA1CA2 | |
| SCHEMBL4423024 | 0.81 | MTNR1B (0.48) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4413402 | 0.81 | GRIN2C (0.42) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4416842 | 0.80 | GRIN2C (0.43) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4416795 | 0.79 | GRIN2C (0.45) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4416993 | 0.78 | GRIN2C (0.45) | GRIN2CMTNR1BTRPV1CA12CA1 | |
| SCHEMBL4411776 | 0.78 | NPC1 (0.53) | GRIN2CMTNR1BCA12CA1CA2 | |
| SCHEMBL13972692 | 0.77 | GRIN2C (0.47) | GRIN2CMTNR1BTRPV1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663983-B1 | N-SUBSTITUTED, 6,8-DIALKOXY-1,2,3,4-TETRAHYDRO-1H-ISOQUINOLINE AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2009-01-21 | — | — | EP | disclosed |