Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052680 | 0.81 | KDM4E (0.42) | KDM4EHTTATMALDH1A1HSD17B10 | |
| SCHEMBL10114036 | 0.79 | KDM4E (0.40) | KDM4EHTTATMALDH1A1HSD17B10 | |
| SCHEMBL13203779 | 0.79 | NPY5R (0.46) | KDM4EHTTATMALDH1A1HSD17B10 | |
| SCHEMBL10133363 | 0.79 | NPY5R (0.46) | KDM4EHTTATMALDH1A1HSD17B10 | |
| SCHEMBL13438695 | 0.79 | PTGER4 (0.45) | KDM4EHTTALDH1A1HSD17B10MAPT | |
| SCHEMBL11934825 | 0.79 | PTGER4 (0.45) | KDM4EHTTALDH1A1HSD17B10MAPT | |
| SCHEMBL13113437 | 0.71 | MAPT (0.47) | KDM4EATMALDH1A1HSD17B10MAPT | |
| SCHEMBL2432582 | 0.68 | ALDH1A1 (0.62) | HTTALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL2432587 | 0.68 | ALDH1A1 (0.62) | HTTALDH1A1MAPTNPSR1HPGD | |
| SCHEMBL10133316 | 0.67 | MAPT (0.44) | KDM4EATMALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |