Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.76 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.76 |
| ▸ | FAAH | O00519 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451203 | 0.90 | KCNK2 (0.77) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL10114761 | 0.83 | KCNK2 (0.66) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL10133403 | 0.83 | KCNK2 (0.66) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL13204323 | 0.83 | KCNK2 (0.66) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL10114367 | 0.83 | KCNK2 (0.66) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL13740811 | 0.81 | KCNK2 (0.67) | KCNK2KCNK4FAAHTP53KDM4E | |
| SCHEMBL3932997 | 0.81 | MAPT (0.78) | KCNK2KCNK4TP53KDM4ENPC1 | |
| SCHEMBL10599193 | 0.80 | NPC1 (0.80) | KCNK2KCNK4TP53KDM4ENPC1 | |
| SCHEMBL11935394 | 0.80 | MAPT (0.58) | KCNK2KCNK4TP53KDM4ENPC1 | |
| SCHEMBL13439107 | 0.80 | MAPT (0.58) | KCNK2KCNK4TP53KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |