Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.78 |
| ▸ | NPC1 | O15118 | 8/20 | 0.78 |
| ▸ | RAB9A | P51151 | 8/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 2/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963239 | 0.93 | MAPT (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL591019 | 0.88 | SMN1; SMN2 (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10599193 | 0.86 | NPC1 (0.80) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL12207363 | 0.86 | SULT1A1 (0.75) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27451359 | 0.85 | NPC1 (0.68) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28669948 | 0.85 | SMN1; SMN2 (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29466151 | 0.85 | SMN1; SMN2 (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL24185813 | 0.84 | SMN1; SMN2 (0.87) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1984153 | 0.84 | MMP2 (0.74) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27451198 | 0.84 | SMN1; SMN2 (0.69) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344055-A4 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008017840-A1 | CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2008-02-14 | — | — | WO | disclosed |
| US-7144738-B2 | Materials for enhancing staining of biopolymers in matrices | WHITNEY SCOTT | 2006-12-05 | — | — | US | disclosed |
| US-20050170517-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION (US) | 2005-08-04 | — | — | US | disclosed |
| US-6878551-B2 | For proteins/polypeptides within polyacrylamide matrix; mass spectrometry | INVITROGEN CORPORATION (US) | 2005-04-12 | — | — | US | disclosed |
| US-20040038418-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-6635489-B2 | Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting | INVITROGEN CORPORATION | 2003-10-21 | — | — | US | disclosed |
| EP-1344055-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020137222-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2002-09-26 | — | — | US | disclosed |
| WO-2002042764-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2002-05-30 | — | — | WO | disclosed |
| US-4324682-A | PRESSURE RUPTURABLE; FOR MARKING AND IDENTIFICATION | AMERICAN CYANAMID COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-3960755-A | Detecting compositions and method of using same | AMERICAN CYANAMID COMPANY (US) | 1976-06-01 | — | — | US | disclosed |