SCHEMBL13974209

SCHEMBL13974209

CN(C)C(=O)CS(N)(=O)=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA4 P43681 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27892095 0.78 POLB (0.43) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL21393555 0.77
SCHEMBL3989018 0.76 ALDH1A1 (0.39) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL21872358 0.76 ALDH1A1 (0.39) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL20760728 0.75 ALDH1A1 (0.44) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL13436390 0.74 ALDH1A1 (0.37) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL12916975 0.74 ALDH1A1 (0.42) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL21393669 0.73 GAA (0.33)
SCHEMBL18924022 0.72 ALDH1A1 (0.40) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL12916989 0.70 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3406142-B1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS CELGENE INT II SARL (CH) 2020-12-23 EP disclosed
WO-2018064356-A1 COMPOUNDS AND METHODS FOR TREATING LUPUS CELGENE INTERNATIONAL II SARL (CH) 2018-04-05 WO disclosed
WO-2015066515-A1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND COMBINATION THERAPY THEREWITH RECEPTOS, INC. (US) 2015-05-07 WO disclosed
WO-2012158550-A2 SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS RECEPTOS, INC. (US) 2012-11-22 WO disclosed