Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1I3 | Q14994 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1565023 | 0.88 | L3MBTL1 (0.76) | L3MBTL1KDM4ESIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL10962630 | 0.77 | MAOB (0.59) | L3MBTL1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7079573 | 0.76 | L3MBTL1 (0.66) | L3MBTL1LMNANPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL6122000 | 0.76 | KDM4E (0.59) | L3MBTL1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1397891 | 0.75 | CYP2A6 (0.49) | L3MBTL1SIGMAR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18768843 | 0.73 | CYP1A2 (0.71) | KDM4ESIGMAR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14433758 | 0.73 | L3MBTL1 (0.58) | L3MBTL1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3940149 | 0.72 | CYP1A2 (0.60) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3390640 | 0.72 | CYP1A2 (0.56) | L3MBTL1KDM4ESIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL1565021 | 0.72 | L3MBTL1 (0.56) | L3MBTL1CYP2C19LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |