Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689720 | 0.86 | TAAR1 (0.54) | TAAR1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL30101707 | 0.85 | TAAR1 (0.61) | TAAR1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL25519810 | 0.85 | TAAR1 (0.61) | TAAR1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8828180 | 0.82 | TAAR1 (0.62) | TAAR1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL31143720 | 0.80 | TAAR1 (0.62) | TAAR1CALM1 | |
| SCHEMBL429483 | 0.79 | TAAR1 (0.67) | TAAR1CALM1 | |
| SCHEMBL25900484 | 0.79 | TAAR1 (0.50) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL108087 | 0.78 | TAAR1 (0.77) | TAAR1CALM1 | |
| SCHEMBL24883650 | 0.78 | TAAR1 (0.53) | TAAR1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11698777 | 0.78 | HTR2A (0.59) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158784-A2 | MODULATORS OF THE NUCLEAR HORMONE RECEPTOR ROR | KAMENECKA THEODORE MARK (US) | 2012-11-22 | — | — | WO | disclosed |