SCHEMBL429483

SCHEMBL429483

CCCc1ccc2c(c1)OCO2

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.67
CALM1 P0DP23 2/20 0.57
SLC6A4 P31645 3/20 0.56
SLC6A2 P23975 2/20 0.56
SLC6A3 Q01959 2/20 0.56
CYP3A4 P08684 2/20 0.55
CYP1A2 P05177 1/20 0.55
MAPT P10636 1/20 0.55
CYP2D6 P10635 1/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
PKM P14618 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29260497 0.98 TAAR1 (0.65) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL4055725 0.89 TAAR1 (0.62) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL29604675 0.89 TAAR1 (0.62) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL8255914 0.88 TAAR1 (0.52) TAAR1CALM1MAPTCYP2D6ALDH1A1
SCHEMBL108087 0.87 TAAR1 (0.77) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL15178307 0.87 TAAR1 (0.61) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL15272035 0.85 TAAR1 (0.59) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL11862122 0.85 TAAR1 (0.59) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL11696002 0.85 TAAR1 (0.59) TAAR1CALM1SLC6A4SLC6A2SLC6A3
SCHEMBL30712274 0.85 TAAR1 (0.59) TAAR1CALM1SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119563631-A Hygienic pesticide composition containing pyriproxyfen and application thereof 广东立威农业科技有限公司 2025-03-07 CN claimed
CN-117343093-A Synthesis method of iron-catalyzed non-activated gem difluoro-bialkylene compound double-silicon-based 山西天宏达安医药科技有限公司 2024-01-05 CN claimed
CN-113866336-B Integrated detection method for safrole and dihydrosafrole in ginger and ginger powder 四川省农业科学院农业质量标准与检测技术研究所 2023-10-10 CN claimed
CN-114586799-A Pine wood nematode disease treating agent and preparation method thereof 南京生兴有害生物防治技术股份有限公司 2022-06-07 CN claimed
EP-3887346-B1 AN EFFICIENT AND ENVIRONMENT FRIENDLY PROCESS FOR CHLOROMETHYLATION OF SUBSTITUTED BENZENES ANTHEA AROMATICS PRIVATE LTD (IN) 2022-05-04 EP claimed
US-11319297-B2 Efficient and environment friendly process for chloromethylation of substituted benzenes ANTHEA AROMATICS PRIVATE LIMITED (IN) 2022-05-03 US claimed
US-20220081406-A1 AN EFFICIENT AND ENVIRONMENT FRIENDLY PROCESS FOR CHLOROMETHYLATION OF SUBSTITUTED BENZENES ANTHEA AROMATICS PRIVATE LIMITED (IN) 2022-03-17 US claimed
CN-113866336-A Integrated detection method for safrole and dihydrosafrole in ginger and ginger powder 四川省农业科学院农业质量标准与检测技术研究所 2021-12-31 CN claimed
EP-3887346-A1 AN EFFICIENT AND ENVIRONMENT FRIENDLY PROCESS FOR CHLOROMETHYLATION OF SUBSTITUTED BENZENES Anthea Aromatics Private Limited (IN) 2021-10-06 EP claimed
WO-2021161083-A1 AN EFFICIENT PROCESS FOR PREPARATION OF ACYL DERIVATIVES OF ALKYLENEDIOXYBENZENES ANTHEA AROMATICS PRIVATE LIMITED (IN) 2021-08-19 WO claimed
CN-1850819-A Method for preparing dihydro safrole KAIDA FINE CHEMICAL CO LTD ZHO (CN) 2006-10-25 CN claimed
EP-1501801-A1 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS UCB, S.A. (BE) 2005-02-02 EP claimed
EP-1140894-B1 PROCESS FOR THE SYNTHESIS OF 5-(ALPHA -HYDROXYALKYL) BENZO 1, 3]DIOXOLS ENDURA SPA (IT) 2003-12-17 EP claimed
WO-2003093237-A1 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS UCB, S.A. (BE) 2003-11-13 WO claimed
US-6355826-B1 HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION THE GOODYEAR TIRE & RUBBER COMPANY 2002-03-12 US claimed
US-6342613-B1 REACTING PYROCATECHOL WITH DIHALO- OR DI-ALKOXYALKANE, ACYLATING BENZO(1,3)DIOXOLE DERIVATIVE FORMED IN PRESENCE OF CATALYST, REDUCING TO 5-(ALPHA-HYDROXYALKYL)BENZO(1,3)DIOXOLE ENDURA S.P.A. (IT) 2002-01-29 US claimed
EP-1140894-A1 PROCESS FOR THE SYNTHESIS OF 5-(ALPHA -HYDROXYALKYL) BENZO 1, 3]DIOXOLS ENDURA S.p.A. (IT) 2001-10-10 EP claimed
WO-2000040575-A1 PROCESS FOR THE SYNTHESIS OF 5-(α -HYDROXYALKYL) BENZO[1, 3]DIOXOLS ENDURA S.P.A. (IT) 2000-07-13 WO claimed
EP-0903338-A2 Synthesis of stable nitrile oxide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-03-24 EP claimed
EP-0547971-A1 Method of hydroxylation of activated aromatic molecules ROUSSEL UCLAF (FR) 1993-06-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081406-A1 AN EFFICIENT AND ENVIRONMENT FRIENDLY PROCESS FOR CHLOROMETHYLATION OF SUBSTITUTED BENZENES F12, CBR3, CYP2F1 TAAR1 1759/4885CALM1 700/4885SLC6A4 3980/4885
US-11319297-B2 Efficient and environment friendly process for chloromethylation of substituted benzenes CBR3, CBR1, F12 TAAR1 1614/4885CALM1 592/4885SLC6A4 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.