SCHEMBL139749

SCHEMBL139749

c1cnc2ccncc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
EGFR P00533 1/20 0.52
NPC1 O15118 2/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 4/20 0.47
MAPT P10636 3/20 0.47
HTT P42858 3/20 0.47
TP53 P04637 2/20 0.47
HSP90AA1 P07900 2/20 0.47
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CASP1 P29466 2/20 0.47
HSP90AB1 P08238 1/20 0.47
ATM Q13315 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP2A6 P11509 2/20 0.44
CYP3A4 P08684 3/20 0.43
PDGFRB P09619 1/20 0.42
PDGFRA P16234 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30917351 1.00 ALDH1A1 (0.58) ALDH1A1EGFRNPC1POLBRAB9A
SCHEMBL30087475 1.00 ALDH1A1 (0.58) ALDH1A1EGFRNPC1POLBRAB9A
Hydrochloric Acid SCHEMBL3326679 0.98 ALDH1A1 (0.56) ALDH1A1EGFRNPC1POLBRAB9A
SCHEMBL28144718 0.98 ALDH1A1 (0.56) ALDH1A1EGFRNPC1POLBRAB9A
Hydrochloric Acid SCHEMBL4774273 0.98 ALDH1A1 (0.56) ALDH1A1EGFRNPC1POLBRAB9A
Formaldehyde SCHEMBL27816605 0.94 ALDH1A1 (0.52) ALDH1A1EGFRNPC1POLBRAB9A
SCHEMBL17840964 0.92 ALDH1A1 (0.56) ALDH1A1EGFRNPC1POLBRAB9A
SCHEMBL27699902 0.90 ALDH1A1 (0.48) ALDH1A1EGFRNPC1POLBRAB9A
Bicarbonate SCHEMBL8411385 0.90 ALDH1A1 (0.48) ALDH1A1EGFRNPC1POLBRAB9A
Quinoline SCHEMBL27569771 0.88 ALDH1A1 (0.63) ALDH1A1EGFRNPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4203 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001877-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-01-01 US claimed
US-20250230168-A1 AZASPIRO WRN INHIBITORS GILEAD SCIENCES, INC. 2025-07-17 US claimed
US-12359118-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-07-15 US claimed
WO-2025137640-A1 AZASPIRO WRN INHIBITORS GILEAD SCIENCES, INC. (US) 2025-06-26 WO claimed
CN-120025306-A Process for the preparation and purification of 4-chloromethyl-5-methyl-1, 3-dioxol-2-one 江苏普信制药有限公司 2025-05-23 CN claimed
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS ROCHE SEQUENCING SOLUTIONS INC (US) 2025-03-06 US claimed
EP-4228630-B1 NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME UNIV FREIBURG ALBERT LUDWIGS (DE) 2025-03-05 EP claimed
US-12232416-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-02-18 US claimed
WO-2025023698-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 진웅산업 2025-01-30 WO claimed
US-20250011293-A1 LEUKOTRIENE SYNTHESIS INHIBITORS NAEGIS PHARMACEUTICALS INC. (CA) 2025-01-09 US claimed
EP-0234516-A1 1,6-Naphthyridine derivatives, process for their preparation and medicine containing them for the treatment of vascular diseases GÖDECKE AKTIENGESELLSCHAFT (DE) 1987-09-02 EP claimed
EP-0222414-A2 Novel organic selenium compounds NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-05-20 EP claimed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US claimed
CN-85106500-A Preparation 1, the method for 6-naphthyridines derivatives and medicinal group and thing 1986-07-23 CN claimed
US-4579679-A Electroactive polymers CHEVRON RESEARCH COMPANY (US) 1986-04-01 US claimed
EP-0173933-A1 1,6-Naphthyridine derivatives, process for their preparation and medicament containing them GÖDECKE AKTIENGESELLSCHAFT (DE) 1986-03-12 EP claimed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP claimed
EP-0096723-A1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS. CHEVRON RES (US) 1983-12-28 EP claimed
WO-1983002368-A1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RES (US) 1983-07-07 WO claimed
EP-0004352-B1 BICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS AROMATIC INGREDIENTS FIRMENICH SA (CH) 1981-11-25 EP claimed