Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.80 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15502379 | 0.90 | KCNH2 (0.84) | KCNH2TLR8TLR7 | |
| SCHEMBL13975892 | 0.89 | KCNH2 (1.00) | KCNH2TLR8TLR7 | |
| SCHEMBL24384587 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7 | |
| SCHEMBL22958997 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7 | |
| SCHEMBL13975908 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7 | |
| SCHEMBL22958985 | 0.82 | KCNH2 (1.00) | KCNH2TLR8TLR7 | |
| SCHEMBL13975716 | 0.82 | KCNH2 (1.00) | KCNH2TLR8TLR7 | |
| SCHEMBL24384698 | 0.79 | KCNH2 (0.70) | KCNH2TLR8TLR7 | |
| SCHEMBL24384584 | 0.77 | KCNH2 (0.85) | KCNH2TLR8TLR7 | |
| SCHEMBL24384693 | 0.77 | KCNH2 (0.85) | KCNH2TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012156498-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN R&D IRELAND (IE) | 2012-11-22 | — | — | WO | disclosed |